MOTS-c 10 mg

Axiolabs MOTS-c 10 mg – Mitochondrial-Derived Peptide

Axiolabs MOTS-c 10 mg is a synthetic peptide corresponding to a mitochondrial-derived peptide encoded within the mitochondrial genome. MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino acid peptide that translocates to the nucleus in response to cellular stress, where it regulates gene expression involved in metabolic homeostasis. Unlike traditional mitochondrial peptides, MOTS-c acts as a hormone-like signaling molecule that influences insulin sensitivity, glucose metabolism, and cellular energy regulation. This mechanism makes it a valuable research tool for studying metabolic disorders, insulin resistance, and mitochondrial-nuclear communication in controlled laboratory settings.

If you are searching for legit MOTS-c for your research protocols, Axiolabs delivers a precisely dosed, lyophilized formulation. For researchers investigating metabolic regulation, AMPK activation, or insulin signaling pathways, MOTS-c provides a novel mitochondrial-derived peptide with growing research literature.

Why Athletes & Bodybuilders Are Researching MOTS-c

Metabolic efficiency, insulin sensitivity, and cellular energy balance are critical areas of study for researchers focused on body composition and exercise metabolism. MOTS-c research explores its effects on glucose uptake, fatty acid oxidation, and metabolic flexibility in research models. The peptide has been shown to activate AMPK (AMP-activated protein kinase), a key regulator of cellular energy homeostasis. For researchers studying metabolic adaptations to exercise or dietary interventions, MOTS-c offers a unique peptide-based approach to investigating mitochondrial-nuclear signaling.

What Makes Axiolabs MOTS-c 10 mg Different?

• ✔ Naturally occurring mitochondrial-derived peptide (16 amino acids)
• ✔ Research literature supporting metabolic regulation and insulin sensitivity
• ✔ Lyophilized formulation for optimal stability and reconstitution accuracy
• ✔ Novel mechanism involving AMPK activation and nuclear gene regulation

Note for researchers: MOTS-c offers a unique mitochondrial-derived peptide for metabolic research. For consistent, reliable results in your studies, always source Axiolabs MOTS-c from verified suppliers. Ensure you are obtaining legit MOTS-c for your critical research protocols.

Product Specifications

Dosage, Reconstitution & Research Guidelines

Reconstitution Instructions

MOTS-c is provided as a lyophilized powder requiring reconstitution before use in research protocols.

• ✔ Add 1-2 mL of Bacteriostatic Water or sterile water for injection to the 10 mg vial
• ✔ Gently swirl the vial to dissolve – do not shake vigorously
• ✔ Calculate final concentration: 10 mg / 2 mL = 5 mg/mL, or 10 mg / 1 mL = 10 mg/mL
• ✔ Use within 30 days when stored at 2–8°C after reconstitution

Research Dosing Guidelines

Based on available research literature, typical MOTS-c dosing in controlled studies falls within the following ranges:

• ✔ 0.5 – 5 mg per kg in animal models (dose-dependent metabolic effects)
• ✔ Each 10 mg vial provides multiple doses depending on protocol
• ✔ Administered via intraperitoneal or subcutaneous injection
• ✔ Research protocols typically evaluate acute or chronic administration effects

Dosing Guide (Insulin Syringe)

Using a 1 mL insulin syringe (U-100) with 2 mL reconstitution volume (5 mg/mL or 5000 mcg/mL concentration):

• ✔ 0.1 mL (10 units) = 500 mcg
• ✔ 0.2 mL (20 units) = 1000 mcg (1 mg)
• ✔ 0.4 mL (40 units) = 2000 mcg (2 mg)
• ✔ 0.6 mL (60 units) = 3000 mcg (3 mg)
• ✔ 1.0 mL (100 units) = 5000 mcg (5 mg)
• ✔ 2.0 mL (200 units) = 10000 mcg (10 mg, full vial)
• ✔ Administer subcutaneously or intraperitoneally as per research protocol

How Researchers Are Using MOTS-c

MOTS-c is an emerging compound in metabolic research, particularly for studies involving insulin sensitivity, glucose homeostasis, and AMPK activation. Its mitochondrial origin makes it unique for investigating mitochondrial-nuclear communication.

Popular research stacks include:

• ✔ MOTS-c + Testaplex C 250 – To investigate combined androgen and metabolic parameters. View Testaplex C 250 →
• ✔ MOTS-c + BPC 157 – For research on metabolic regulation and tissue repair. View BPC 157 5 mg →
• ✔ MOTS-c + Ipamorelin – To study combined metabolic and somatotropic research protocols. View Ipamorelin 5 mg →

Research Protocol Example (4-Week Study)

• ✔ Days 1-28: MOTS-c 1-2 mg administered 2-3 times weekly subcutaneously
• ✔ Days 1-28: Metabolic assessments including glucose tolerance and insulin sensitivity
• ✔ Washout period: Minimum 48-72 hours between final dose and terminal measurements

Important Considerations

• 🔬 MOTS-c is a mitochondrial-derived peptide encoded within the mitochondrial genome
• 💧 Reconstituted solution should be clear and particle-free; do not use if discolored
• ⚠️ AMPK activation pathways require careful protocol design for reproducible results
• 📦 Consistent dosing schedule improves data reliability in metabolic studies
• 📦 Always source Axiolabs MOTS-c from authorized distributors to ensure peptide integrity

Lab Verification – Third-Party Test Results

At Axiolabs, every batch of MOTS-c is scheduled for independent third-party HPLC-MS testing to verify identity, purity, and concentration. Below is the status of the latest lab analysis.

What Will Be Tested?

• ✔ Identity confirmation via mass spectrometry (MS) and sequence analysis
• ✔ Purity assessment using High-Performance Liquid Chromatography (HPLC)
• ✔ Accurate peptide content (target: 10 mg per vial)
• ✔ Residual solvent, endotoxin, and bioburden screening

Why Third-Party Testing Matters

With the proliferation of underdosed and mislabeled research peptides, independent laboratory verification is the only definitive method to confirm you are working with authentic, high-purity materials. Axiolabs MOTS-c must meet strict specifications to ensure research validity. Axiolabs is dedicated to full disclosure, and all batch-specific COAs will be hosted here as they become available.

For more information on MOTS-c's mechanism of action and research applications, refer to this PubMed study on mitochondrial-derived peptides.

Shipping & Product Authenticity

What to Expect

• ✔ Orders processed within 24–48 hours after payment confirmation
• ✔ USA Domestic shipping via USPS/UPS/FedEx – tracking included
• ✔ International tracking available (update frequency varies by destination)
• ✔ Lyophilized peptides are shipped in protective, temperature-controlled packaging

How to Verify You Have Legit MOTS-c

Counterfeit research peptides are a genuine concern. Here's how to confirm you are using authentic Axiolabs MOTS-c:

• ✔ Holographic authentication seal – each Axiolabs vial features a tamper-evident holographic seal
• ✔ Unique serial number – verify the vial's serial number through the official Axiolabs verification portal
• ✔ Batch traceability – match the batch number on your vial to the lab test results (once published)
• ✔ Original packaging integrity – sealed vial with clear Axiolabs branding and lot information

For complete delivery details, tracking policy, international customs, and reshipment terms, please see our Shipping Info page.

Storage Guidelines

Storage Recommendations – Lyophilized Powder (Before Reconstitution)

• ✔ Store at 2–8°C (36–46°F) – refrigerated temperature
• ✔ Keep in original packaging, away from light
• ✔ Stable for up to 12 months when stored properly
• ✔ Do not freeze the lyophilized powder
• ✔ Protect from moisture and humidity

Storage Recommendations – Reconstituted Solution (After Reconstitution)

• ✔ Refrigerate at 2–8°C (36–46°F) immediately after reconstitution
• ✔ Use within 30 days when stored at refrigerated temperature
• ✔ Discard any unused solution after 30 days
• ✔ Avoid repeated freeze-thaw cycles
• ✔ Store in original vial with sterile rubber stopper sealed

What to Avoid

• ❌ Freezing the lyophilized powder – may damage peptide structure
• ❌ Leaving reconstituted peptide at room temperature for extended periods
• ❌ Vortexing or shaking vigorously – gentle swirling only
• ❌ Using peptide that appears cloudy or contains particulate matter after reconstitution
• ❌ Storing in bathroom or near heat sources

Inspection Before Use

Before using in your research, always inspect the product:

• ✔ Lyophilized powder should be a white to off-white cake or powder at the bottom of the vial
• ✔ Vial seal must be intact – do not use if flip-off cap is broken or missing
• ✔ Reconstituted solution should be clear and particle-free
• ✔ Check batch number and serial number for authenticity before use

Keep out of reach of children and unauthorized personnel. Always follow your institution's laboratory safety and chemical hygiene guidelines for peptide handling.

Frequently Asked Questions