MOTS-C 10 mg

Dragon Pharma MOTS-C 10 mg – Mitochondrial-Derived Peptide for Metabolic Research

Dragon Pharma MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a naturally occurring mitochondrial-derived peptide encoded within the mitochondrial genome. Unlike nuclear-encoded peptides, MOTS-C is translated from mitochondrial DNA and acts as a cellular signaling molecule that regulates metabolic homeostasis. It has been shown in research to improve insulin sensitivity, enhance glucose metabolism, and promote energy balance through AMPK activation and its effects on the folate-methionine cycle.

If you're looking for legit MOTS-C for research purposes, this peptide has gained significant attention as a novel regulator of metabolism, distinct from traditional metabolic compounds. For researchers studying mitochondrial biology, insulin resistance, obesity, or aging-related metabolic decline, MOTS-C represents a unique mitokine tool worth exploring.

Why Athletes & Bodybuilders Are Researching MOTS-C

Metabolic efficiency and insulin sensitivity are critical for body composition and athletic performance. MOTS-C research suggests it may enhance glucose uptake, increase metabolic rate, and improve exercise capacity — without the side effects associated with traditional stimulants. As a naturally occurring mitochondrial signaling peptide, it offers a novel pathway for studying metabolic optimization. For researchers investigating metabolic flexibility, exercise mimetics, or age-related metabolic changes, MOTS-C provides a unique mitochondrial-derived research tool.

What Makes Dragon Pharma MOTS-C Different?

• ✔ Mitochondrial-derived peptide — encoded by mitochondrial DNA (unique origin)
• ✔ Regulates insulin sensitivity and glucose metabolism via AMPK
• ✔ Influences the folate-methionine cycle (one-carbon metabolism)
• ✔ Researched for metabolic adaptation, exercise capacity, and longevity

Note for researchers: MOTS-C is a mitochondrial peptide with unique biology distinct from nuclear-encoded peptides. For best results in your research, follow established protocols and always source MOTS-C from verified suppliers like Dragon Pharma.

Product Specifications

Dosage, Reconstitution & Research Guidelines

Reconstitution Instructions (10 mg Vial)

MOTS-C comes as a lyophilized powder in a 2 mL sterile vial. You'll need bacteriostatic water to reconstitute it properly.

• ✔ Add 2 mL of bacteriostatic water to the vial
• ✔ Final concentration: 5 mg per mL (5000 mcg/mL)
• ✔ Gently swirl — do not shake
• ✔ Refrigerate after reconstitution and use within 14 days

Need bacteriostatic water for your research? Get it here →

Typical Research Dosing

Based on available research literature, typical MOTS-C dosing in animal studies falls in this range:

• ✔ 5 – 20 mg per kg in research models (dose-dependent metabolic effects)
• ✔ Typical research dose: 0.5 – 2.0 mg per injection
• ✔ One 10 mg vial provides approximately 5-20 research doses depending on dose
• ✔ Dosing frequency typically daily or every few days depending on study design

Insulin Syringe Dosing Guide

Using a standard 1 mL (100 unit) insulin syringe with MOTS-C reconstituted to 5 mg/mL (5000 mcg/mL):

• ✔ 0.05 mL (5 units) = 250 mcg
• ✔ 0.10 mL (10 units) = 500 mcg
• ✔ 0.20 mL (20 units) = 1000 mcg (1 mg)
• ✔ 0.40 mL (40 units) = 2000 mcg (2 mg)
• ✔ Administer subcutaneously or intraperitoneally depending on protocol

How Researchers Are Using MOTS-C

MOTS-C is a novel mitochondrial-derived peptide with distinct metabolic mechanisms. Researchers studying insulin sensitivity, glucose metabolism, mitochondrial function, and metabolic adaptation often utilize MOTS-C in their protocols.

Popular research stacks include:

• ✔ MOTS-C + AICAR — for complementary AMPK activation research. View AICAR →
• ✔ MOTS-C + GW501516 (Cardarine) — for metabolic and endurance research. View GW501516 →
• ✔ MOTS-C + BPC 157 — for metabolic + tissue repair research. View BPC 157 →

Research Protocol Example (4-8 Weeks)

• ✔ Weeks 1–8: MOTS-C 0.5-1.0 mg daily or every other day subQ
• ✔ Weeks 1–8: AICAR 50-100 mcg daily (optional stack for AMPK research)
• ✔ Post-cycle observation: 2-4 weeks off before next research phase

Important Considerations

• 🔬 MOTS-C is encoded by mitochondrial DNA, not nuclear DNA — unique among research peptides
• 💧 Regulates the folate-methionine cycle (one-carbon metabolism) in addition to AMPK
• ⚠️ Researched for metabolic adaptation, insulin sensitivity, and exercise capacity
• 📦 Always source MOTS-C from verified suppliers like Dragon Pharma

Lab Verification – Third-Party Testing (Coming Soon)

At Dragon Pharma, every batch of MOTS-C is scheduled for independent third-party HPLC testing to verify purity, mass, and sterility. The report for the current batch is in progress and will be published here as soon as it's available.

What Will Be Tested?

Why Third-Party Testing Matters

With the rise of counterfeit research peptides, independent lab verification is the only way to confirm you're getting what you paid for. MOTS-C should meet strict purity and mass standards. Dragon Pharma commits to full transparency — as soon as each batch is tested, the COA will appear here with:

• ✔ HPLC chromatogram (visible peak purity)
• ✔ Measured mass vs label claim (10 mg)
• ✔ Batch number for traceability
• ✔ Test date and lab accreditation

For more information on MOTS-C research and mitochondrial biology, refer to this PubMed study on MOTS-C and metabolic regulation.

Shipping & Product Authenticity

What to Expect

• ✔ Orders processed within 24–48 hours after payment confirmation
• ✔ USA Domestic shipping via USPS/UPS/FedEx — tracking included
• ✔ International tracking available (update frequency varies by destination)
• ✔ Cold-chain packaging not required for lyophilized peptide before reconstitution, but vials are shipped in protective padding

How to Verify You Have Legit MOTS-C

Counterfeit research peptides are a real problem. Here's how to confirm you're getting authentic Dragon Pharma MOTS-C:

• ✔ QR code verification — each box includes a unique QR code. Scan it to verify the batch on Dragon Pharma's official database
• ✔ Scratch-off serial number — reveals a one-time use code for online verification
• ✔ Batch traceability — match the batch number on the vial to our system (lab report coming soon)
• ✔ Original crimp seal — intact, sterile vial with Dragon Pharma labeling

For complete delivery details, tracking policy, international customs, and reshipment terms, please see our Shipping Info page.

Storage Guidelines

Before Reconstitution (Lyophilized Powder)

• ✔ Store at 2–8°C (36–46°F) — standard refrigerator temperature
• ✔ Do not freeze the lyophilized powder
• ✔ Keep in original packaging, away from light
• ✔ Stable for up to 12 months when refrigerated properly
• ✔ Avoid repeated temperature changes (don't take in and out of fridge unnecessarily)

After Reconstitution (Mixed with Bacteriostatic Water)

• ✔ Store at 2–8°C (36–46°F)
• ✔ Use within 14 days of reconstitution
• ✔ Do not freeze after reconstitution — freezing can damage peptide structure
• ✔ Keep vial upright and sealed between uses
• ✔ Avoid direct light exposure

What to Avoid

• ❌ Freezing (before or after reconstitution — damages peptide bonds)
• ❌ Leaving at room temperature for extended periods (>24 hours)
• ❌ Shaking the vial — swirl gently instead
• ❌ Using cloudy or particulated solution after reconstitution
• ❌ Storing in bathroom or near heat sources

Inspection Before Use

Before using in your research, always inspect the vial:

• ✔ Lyophilized powder should appear as a white, intact cake or powder — not yellow, clumped, or melted
• ✔ After reconstitution, solution should be clear and particle-free
• ✔ Crimp seal must be intact — do not use if seal is broken or missing
• ✔ Check batch number and QR code for authenticity before use

Keep out of reach of children and unauthorized personnel. Follow institutional laboratory safety guidelines for handling research peptides.

Frequently Asked Questions